Coenzyme Q10 (ubiquinone and ubiquinol) — evidence review — Supplement & Protocol Data

Heart-failure symptoms, hospitalisation, and death (the Q-SYMBIO claim).
Relief of statin-associated muscle symptoms (pain, cramp, weakness) and better statin adherence.
Migraine prophylaxis: fewer attacks, shorter attacks, less severe attacks.
Male fertility: better semen parameters and more pregnancies.
Athletic / exercise performance (VO2max, time to exhaustion, power, less fatigue).
Higher plasma CoQ10 (sold as if it were the clinical outcome).
CoQ10 100 mg + PQQ 10 mg as a mitochondrial “stack” (claim only; PQQ not reviewed).

Coenzyme Q10 (ubiquinone and ubiquinol) — evidence review