What it is
Regulatory status: FDA-approved prescription medicine for hypertension and selected heart-failure indications
Mechanism evidence: human
At a glance
What it is, why people use it, the evidence, and what to know before trying it.
Why people use it
- Blood-pressure reduction
- Heart-failure treatment in labelled populations
- Kidney protection claims
- Longevity or neuroinflammation claims
Evidence at a glance
Evidence and approval are strong for hypertension and specified heart-failure uses. Brain-inflammation and general longevity claims are not established clinical indications and should not be inferred from blood-pressure benefit.
Confidence: strong
Clinical safety
Contraindications, interactions and clinical cautions from reviewed sources.
The US label carries a boxed warning for fetal toxicity. Risks include hypotension, increased potassium and kidney-function changes; monitoring and medication-interaction review are important, especially with other renin-angiotensin drugs, potassium products, NSAIDs or lithium.
Forms and variants
This review does not automatically apply to:
- candesartan with hydrochlorothiazide
- other angiotensin receptor blockers
Seen in protocols
Public protocols that include Candesartan. Open one to see the full context and source.