What it’s for
- Studied for cognitive symptoms
A magnesium salt marketed for cognitive and sleep benefits.
Purpose, evidence and practical considerations.
A small trial of a magnesium L-threonate formula reported cognitive improvements. Replication and clinical outcomes remain limited; animal findings about brain magnesium do not establish the same effect in people.
Confidence: weak
Human safety evidence is limited and mostly short term. Magnesium supplements can cause diarrhea and may accumulate with significant kidney impairment; they can also reduce absorption of some antibiotics and other medicines when taken together.
Magnesium L-threonate is a low-elemental magnesium salt promoted for brain delivery. The frequently cited increase in cerebrospinal-fluid magnesium comes from animals; human trials have not directly measured higher brain or CSF magnesium after oral use.
Regulatory status: supplement (oral mineral / organic salt). Not a prescription drug. Not a device, habit, or measurement. Neurocentria is developing the same ligand as a drug candidate (MMFS / L-TAMS) for ADHD, depression, and Alzheimer’s — that is a different regulatory track from the OTC Magtein bottle
The evidence on this page does not automatically apply to:
How people use it, with their schedules, context and original sources.
145 mg · 30–60 min before bed
nightly · night stack
sleep, and part of his ~1 g elemental magnesium target
Amount and timing patterns reported in public protocols; these are observations, not instructions. Private and hidden usage is excluded.
daily
Brand variants reported in public protocols. Private entries are excluded, and inclusion is not an endorsement.
These share a protocol with this intervention. This does not establish that they work together or are suitable alternatives.
Daily · night (implied by the sleep portion of his roll call)
sleep; part of the Momentous Performance Stack he credited with "mental, physical, and sleep benefits"