What it is
Regulatory status: the former FDA-approved Geref product was discontinued; current compounded sermorelin is not an FDA-approved finished drug
Evidence basis: Human clinical evidence
Sermorelin stimulates pituitary growth-hormone release when the pituitary axis can respond, increasing downstream IGF-1. That pharmacology does not establish benefit for sleep, recovery, anti-aging or bodybuilding in healthy adults.
What it is, why people use it, the evidence, and what to know before trying it.
Regulatory status: the former FDA-approved Geref product was discontinued; current compounded sermorelin is not an FDA-approved finished drug
Evidence basis: Human clinical evidence
Contraindications, interactions and clinical cautions from reviewed sources.
Sermorelin can cause injection reactions, flushing, headache, dizziness and hormone-related adverse effects. Compounded products add sterility, identity and dosing uncertainty; use requires licensed clinical oversight.
This review does not automatically apply to:
Public protocols that include Sermorelin. Open one to see the full context and source.
Stopped because it "obliterated my rapid eye movement sleep" despite more deep sleep on Eight Sleep. He added, "I'm not on growth hormone." FoundMyFitness, 12 Jun 2024.
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