Longevity Supplement Stack

Sinclair's NAD+/sirtuin-focused supplement and prescription protocol. Core thesis: activate survival pathways through NMN, resveratrol, and fasting mimetics.

10 supplements · 3 prescriptions

David Sinclair

Professor of Genetics at Harvard Medical School, author of NYT bestseller "Lifespan," co-director of Paul F. Glenn Center for Biology of Aging.

Supplement

daily

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Protocol Actions

Supplements (10)

Nicotinamide Mononucleotide (NMN)

daily · Morning, mixed in yogurt

Resveratrol

daily · Morning, with fat (yogurt) for absorption

TMG (Trimethylglycine)

daily · Daily

500-1,000 mg

Spermidine

daily · Morning

1-2 mg

Quercetin

daily · Morning

500 mg

Fisetin

daily · Morning

500 mg

Vitamin D3

daily · Daily

4,000-5,000 IU

Vitamin K2

daily · Daily

180-360 mcg

Taurine

daily · Daily

Low-dose Aspirin

daily · Daily

83 mg

Prescriptions (3)

Metformin

daily · Evening

800-1,000 mg

Statin (high dose)

daily · Daily

Dose unspecified

Rapamycin

daily · Weekly

Dose unconfirmed

longevity

NAD+

sirtuins

anti-aging