What it is
Regulatory status: dietary supplement; not FDA-approved to treat jet lag, dementia or stress disorders
Mechanism evidence: human
At a glance
What it is, why people use it, the evidence, and what to know before trying it.
Why people use it
- Cognitive support
- Stress response
- Jet-lag support
Evidence at a glance
Evidence is limited and population-specific. There is no strong basis for treating phosphatidylserine as a proven jet-lag intervention, and mixed formulas cannot establish the effect of phosphatidylserine alone.
Confidence: weak
Safety & interactions
Known side effects, interactions and use limits from reviewed sources.
Short studies generally report mild gastrointestinal or sleep effects, but long-term data and interaction data are limited. Soy-derived products may matter for allergies.
Forms and variants
This review does not automatically apply to:
- phosphatidylcholine
- serine
- multi-ingredient stress or sleep blends
Seen in protocols
Public protocols that include Phosphatidylserine. Open one to see the full context and source.