What it’s for
- Magnesium supplementation
- studied for sleep
Magnesium bound to glycine, often labelled magnesium bisglycinate.
Purpose, evidence and practical considerations.
A four-week trial in 155 adults with poor sleep found a small improvement in self-reported insomnia scores over placebo. This is preliminary evidence, not proof that it is the best magnesium form for sleep.
Confidence: weak
Supplemental magnesium can cause diarrhea, nausea and cramping. Toxicity risk rises with kidney impairment. Magnesium reduces absorption of tetracycline and quinolone antibiotics and bisphosphonates unless doses are separated.
Magnesium supports normal neural and muscle function, while the glycine ligand may influence tolerability and contributes glycine. A special sleep advantage over other forms is not established, and fully reacted bisglycinate differs from oxide-buffered products.
Regulatory status: supplement (oral mineral / amino-acid chelate). Not a prescription drug. Not a device, habit, or measurement
The evidence on this page does not automatically apply to:
How people use it, with their schedules, context and original sources.
200-400mg · Daily or evening
Powers 600+ enzymatic reactions, sleep, muscle function
200 mg · 30–60 min before bed
Amount and timing patterns reported in public protocols; these are observations, not instructions. Private and hidden usage is excluded.
daily
Brand variants reported in public protocols. Private entries are excluded, and inclusion is not an endorsement.
These share a protocol with this intervention. This does not establish that they work together or are suitable alternatives.
120 mg · Daily · before bed