Dr. Mark Hyman's Core Supplement Stack
Comprehensive supplement protocol for longevity, metabolic health, and optimal function. Emphasizes high-quality, bioavailable forms.
Shared protocol · For reference, not advice
Interventions
Supplements
- Multivitamin
2-6 capsules · Daily · Daily with meals
Foundation supplement - safety net for nutritional gaps
- Vitamin D3
2,000-5,000 IU · Daily
Immune function, metabolic health, hormone balance. Adjust based on blood levels.
- Magnesium Glycinate
200-400mg · Daily · Daily or evening
Powers 600+ enzymatic reactions, sleep, muscle function
- Alpha-Lipoic Acid (ALA)
300-600mg · Daily · Daily (split doses)
Blood sugar regulation, antioxidant, liver support
- B-Vitamin Complex (Methylated)
2 capsules · Daily · Daily with meals
Homocysteine control, methylation support, energy
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- v1Current versionFebruary 22, 2026